Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272490 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
Four novel polyisoprenylated benzophenone derivatives, paucinones A-D (1-4), were isolated from the leaves of the plant Garcinia paucinervis. Paucinones A-C (1-3) contained an unexpected cyclohexane-spiro-tetrahydrofuran moiety. A 1-methylene-3,3-dimethylcyclohexane group never reported before was found in the structure of paucinone D (4). The structures of these compounds were elucidated with spectroscopic evidences. The relative stereochemistries of 1-4 were determined by NOESY correlations. These compounds showed significant cytotoxicities against HeLa cells.
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Organic Chemistry
Authors
Xue-Mei Gao, Ting Yu, Fanny Shuk Fan Lai, Jian-Xin Pu, Chun-Feng Qiao, Yan Zhou, Xin Liu, Jing-Zheng Song, Kathy Qian Luo, Hong-Xi Xu,