| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272553 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A series of 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylates are synthesized by a unique reaction of triphenyl verdazyl radical with di-substituted electron deficient alkyne carboxylates. This transformation allows for the quick synthesis of this class of compounds in just three steps starting from a hydrazone. A radical mechanism that is consistent for the substitution patterns observed in the series of compounds made is proposed. The final product is obtained by a subsequent retro-Diels-Alder reaction.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Matthew Bancerz, Ernest Prack, Michael K. Georges,