| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272624 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
An efficient synthesis toward 2-alkyl substituted oxazoles has been achieved through Suzuki cross-coupling reaction. Treatment of various alkyl iodides with 9-MeO-BBN, followed by in situ palladium-catalyzed carbon-carbon formation with 2-iodooxazoles obtained the 2-alkyl substituted oxazoles in good to excellent yields. Regioselective C2-alkylation on 2,4-di-iodooxazole under the same reaction conditions was firstly disclosed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xing Zhang, Jun Liu, Yi Liu, Yuguo Du,