| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272832 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nobuhiro Kanomata, Gou Mishima, Jun Onozato,