| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272839 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A protocol for the copper-catalyzed C-S bond formation between aryl, alkyl, or heteroaryl thiols and aryl or heteroaryl halides is reported. The reaction is catalyzed by Cu2O which shows the highest catalytic activity with ethyl 2-oxocyclohexanecarboxylate ligand in DMSO at 80 °C. The corresponding coupling products are obtained with good to excellent yields under relatively mild reaction conditions with good chemoselectivity and functional group tolerance.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hua-Jian Xu, Xiao-Yang Zhao, Jin Deng, Yao Fu, Yi-Si Feng,