Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272910 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
An efficient route for the synthesis of sterically hindered substituted and unsubstituted 2,6-dioxo tetrahydropyrimidines from amine 1 is described. These analogs are active against HCV NS3 serine protease. The biological data for some of the representative examples are also reported.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Latha G. Nair, Stephane Bogen, Ronald J. Doll, N.-Y. Shih, F. George Njoroge,