Article ID Journal Published Year Pages File Type
5272919 Tetrahedron Letters 2010 4 Pages PDF
Abstract
A one-pot three-component condensation of an aldehyde, malononitrile, and thiophenol has been achieved by conventional and ultrasound method. The reaction was catalyzed by boric acid in aqueous medium. This protocol afforded corresponding 2-amino-3,5-dicarbonitrile-6-thio-pyridines in shorter reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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