Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272919 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A one-pot three-component condensation of an aldehyde, malononitrile, and thiophenol has been achieved by conventional and ultrasound method. The reaction was catalyzed by boric acid in aqueous medium. This protocol afforded corresponding 2-amino-3,5-dicarbonitrile-6-thio-pyridines in shorter reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents.
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Authors
Pravin V. Shinde, Swapnil S. Sonar, Bapurao B. Shingate, Murlidhar S. Shingare,