Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272922 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
2-Amino-8-oxo-tetrahydro-4H-chromene-3-carbonitriles were synthesized for the first time from a tandem Michael addition-cyclization reaction between cyclohexane-1,2-dione and benzylidenemalononitriles. An enantioselective synthesis of these compounds was achieved in moderate ee values (up to 63% ee) by using a cinchona alkaloid-derived thiourea catalyst.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Derong Ding, Cong-Gui Zhao,