| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272940 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A tandem cycloisomerization/Friedel-Crafts alkylation of indoles has been achieved in a one-pot process to produce 2,5-disubstituted furans using gallium-catalyzed sequential nucleophilic addition onto metal-activated 1-alkynyl-2,3-epoxy acetates. The reaction proceeds efficiently under mild conditions with complete regioselectivity to afford the substituted furan derivatives in good yields with high diversity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
B.V. Subba Reddy, B. Bramha Reddy, K.V. Raghavendra Rao, J.S. Yadav,