| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272978 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A total synthesis of bioactive tetracyclic natural product paracaseolide A, embodying an architecturally unusual oxa-bowl framework, has been accomplished from commercially available 5-methyl-2-furfural. The key step involving a thermal [4+2]-dimerization of an appropriately crafted 5-methyl-3-alkenylbutenolide is shown to proceed in a stepwise manner.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
