Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272980 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
We report herein the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from amidoximes and substituted or unsubstituted benzoyl cyanides under microwave irradiation. Substituted or unsubstituted O-carboxyphenyl amidoxime is a key intermediate of this alternative method developed for the synthesis of these heterocycles. These reactions employ simple synthetic protocols devoid of lengthy purification procedures and proceed with good yield.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shivaji Kandre, Pundlik Rambhau Bhagat, Rajiv Sharma, Amol Gupte,