| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273012 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
To develop a small molecule-based biomarker for in vivo apoptosis imaging, a dansyled amino acid derivative (BNSBA) was designed and synthesized in good yield. The biological evaluation demonstrated that BNSBA selectively binds to apoptotic cancer cells and is localized within the cytoplasm of cells that bound annexin V on the plasma membrane.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wenbin Zeng, Weimin Miao, George Kabalka, Michael Le Puil, John Biggerstaff, David Townsend,