Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273021 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Stereoselective synthesis of (â)-centrolobine, an anti-Leishmania agent, was accomplished via an intramolecular Barbier-type reaction of iodo-ester with n- or t-butyllithium followed by Lewis acid-promoted Et3SiH reduction of the resulting hemiacetal.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Toshiharu Takeuchi, Miyuki Matsuhashi, Tadashi Nakata,