Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273078 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
Both nitrile and arylamino groups containing pyridine derivatives are synthesized from commercially available nitrile substituted pyridyl chlorides via a palladium-BINAP catalyst (the second generation catalyst for the amination) in moderate to good yields. The mild conditions permit the presence of base sensitive functional groups. Noteably, the halogen atoms linked to the aromatic ring were maintained in the structures of the products under the amination reaction conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shuo Guo, Yaping Wang, Chunxia Sun, Jingya Li, Dapeng Zou, Yangjie Wu, Yusheng Wu,