Article ID Journal Published Year Pages File Type
5273082 Tetrahedron Letters 2013 5 Pages PDF
Abstract

The ZnCl2-catalyzed three-component synthesis of pyrano[3,2-c]quinolin-5(6H)-ones from the domino reactions of 4-hydroxy-1-methylquinolin-2(1H)-one, nitroketene N,S-methylacetal, and aromatic aldehydes in ethanol in good yields is described. This domino transformation leads to the formation of one ring by creation of two C-C bonds and one C-O bond in a single synthetic operation.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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