| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273092 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
The chemical sulfation of β-resorcylic acid esters was investigated by applying state of the art procedures for the synthesis and deprotection of 2,2,2-trichloroethyl protected sulfates as appropriate intermediates. The selectivity of monosulfation was studied and reaction optimization was performed considering the effect of the solvent, different bases as well as the sulfation reagent itself. Finally the obtained protocols were applied for the first synthesis of zearalenone-14-sulfate (ammonium salt), an important conjugated (masked) mycotoxin, as reference material for further investigations in the field of bioanalytics as well as toxicology.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hannes Mikula, Barbara Sohr, Philipp Skrinjar, Julia Weber, Christian Hametner, Franz Berthiller, Rudolf Krska, Gerhard Adam, Johannes Fröhlich,