| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273133 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Aldehyde, homoallylic alcohol, and alkyne undergo smooth Prins-type cyclization in the presence of BF3·OEt2/CuCl (10 mol % each) in dichloromethane under mild reaction conditions to afford 4-phenacyl tetrahydropyran derivatives in good yields. This method is highly stereoselective, affording cis-tetrahydropyrans exclusively. The salient features of this method are high conversions, mild reaction conditions, short reaction times, high selectivity, and operational simplicity.
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Related Topics
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Chemistry
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Authors
J.S. Yadav, B.V. Subba Reddy, Y. Jayasudhan Reddy, Bh. Phaneendra Reddy, P. Adinarayana Reddy,