Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273143 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The method involves CDI mediated amidation under solvent-free conditions. The protocol is green, simple, and scalable and has broad structural applicability. The protocol has also been used for BOC protection of amine. The protocol has reduced the time for CDI mediated amidation from 2-4Â h to 5-10Â min without the use of any dry organic solvent and nitrogen atmosphere.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sanjeev K. Verma, Ramarao Ghorpade, Ajay Pratap, M.P. Kaushik,