Article ID Journal Published Year Pages File Type
5273143 Tetrahedron Letters 2012 4 Pages PDF
Abstract

The method involves CDI mediated amidation under solvent-free conditions. The protocol is green, simple, and scalable and has broad structural applicability. The protocol has also been used for BOC protection of amine. The protocol has reduced the time for CDI mediated amidation from 2-4 h to 5-10 min without the use of any dry organic solvent and nitrogen atmosphere.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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