Article ID Journal Published Year Pages File Type
5273182 Tetrahedron Letters 2008 4 Pages PDF
Abstract

Herein we report an efficient method for synthesis of β-alkylated and β,β-dialkylated α-iodo enol ethers in water. Radical addition in aqueous medium of ethyl iodoacetate, iodoacetonitrile, and iodoacetamide to ynol ethers leads to α-iodo enol ethers with moderate to excellent yields and high stereoselectivities.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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