Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273202 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
An efficient, one-pot Friedel-Crafts acylation/hydrolysis reaction promoted by the acidic ionic liquid 1-ethyl-3-methylimidazolium chloroaluminate (generated from 1-ethyl-3-methylimidazolium chloride (EmimCl) and aluminum chloride (X(AlCl3), mole fraction XÂ =Â 0.75) for the formation of 3-glyoxylic acid derivatives of electron-deficient, substituted 4- and 6-azaindoles is described.
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Organic Chemistry
Authors
Kap-Sun Yeung, Zhilei Qiu, Michelle E. Farkas, Qiufen Xue, Alicia Regueiro-Ren, Zhong Yang, John A. Bender, Andrew C. Good, John F. Kadow,