Article ID Journal Published Year Pages File Type
5273226 Tetrahedron Letters 2009 4 Pages PDF
Abstract

An easy approach to mono- and bicyclic derivatives of 5,6-dihydro-1H-pyridine-2-thione via a one-pot ring closing metathesis (RCM) of dialkenoic amides and thionation using Lawesson's reagent, followed by isomerization of the 3,6-dihydro-isomer (if necessary), is described. The appreciable differences in the reactivity of diallylic amides in RCM reactions are discussed.

Graphical abstractDownload full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
,