Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273230 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
4-Hydroxy-prolinamide alcohol with different noncoordination sites as a molecule showed excellent asymmetric catalytic activity in both the Michael reaction (up to 98% ee) and the direct aldol reaction (up to >99% ee), and the catalyzing reactions with high enantioselectivity are supported by a DFT theoretical study of their transition state.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yuko Okuyama, Hiroto Nakano, Yuki Watanabe, Mika Makabe, Mitsuhiro Takeshita, Koji Uwai, Chizuko Kabuto, Eunsang Kwon,