Article ID Journal Published Year Pages File Type
5273329 Tetrahedron Letters 2013 4 Pages PDF
Abstract

Concise and efficient three-component domino reactions to highly substituted tetrahydroindole derivatives promoted by p-TsOH have been developed under microwave irradiation condition. The direct C3-alkoxylation of indole framework was achieved in a one-pot operation. The reaction proceeds at fast rates and can be finished within 30 min, which makes workup convenient to give good chemical yields.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry