Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273334 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
Aldehydes and ketones were synthesized from their respective acid chlorides via a one-pot protocol. Morpholine amide intermediates that were readily prepared by the aminolysis of various acid chlorides with diisobutyl(morpholino)aluminum smoothly reacted with the reducing agent LDBMA and the organolithium reagents under mild reaction conditions (0 °C), giving almost excellent product yields of up to 95%.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jae Kyo Park, Won Kyu Shin, Duk Keun An,