Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273381 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
The enzymatic reaction of copalyl diphosphate (CDP), ent-CDP, syn-CDP, and tuberculosinyl diphosphate with the CYC2 enzyme from Kitasatospora griseola afforded sclarene, biformene, and novel diterpenes having a buta-1,3-diene moiety in the side chain. The substrate specificity of the CYC2 is discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chiaki Nakano, Tsutomu Hoshino, Tsutomu Sato, Tomonobu Toyomasu, Tohru Dairi, Takeshi Sassa,