Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273387 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
The domino-Knoevenagel-hetero-Diels-Alder reaction of O-propargylated salicylaldehyde and 1-methylindoline-2-thione in aqueous medium in the absence of Lewis acid has been described for the synthesis of hitherto unreported indole-annulated pentacyclic heterocycles containing oxygen, nitrogen and sulfur. This methodology involves only one step and easy work-up procedure to give the products in 72-80% yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K.C. Majumdar, Abu Taher, Sudipta Ponra,