| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273418 | Tetrahedron Letters | 2012 | 4 Pages |
Penispirolloid A (1), a novel alkaloid possessing a unique spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain, Penicillium sp. OUCMDZ-776. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 μg/ml. Plausible biogenesis of compound 1 was also proposed.
Graphical abstractPenispirolloid A (1), a new alkaloid possessing a unique spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain, Penicillium sp. OUCMDZ-776 strain. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 μg/ml.Download full-size image
