β-Strand mimetics: formation of bend-strands in oligomers of enantiomeric β-amino acids

Oligomers comprising of enantiomeric cis-oxo-β-norbornene amino acid [2R,3S] and [2S,3R] residues at alternate positions were synthesized and characterized by extensive NMR and MD studies, which showed robust bend-strand secondary structures.

Graphical abstractOligomers comprising of enantiomeric cis-exo-β-norbornene amino acids [2R,3S] and [2S,3R] residues at alternate positions form robust β-strand mimetics with a curved backbone.Download full-size image