| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273531 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Chiral 2-azanorbornyl-3-methanol is used as an organocatalyst for the highly enantioselective direct vinylogous Michael addition reaction of vinyl malononitriles to α,β-unsaturated aldehydes. In many cases, the products can be obtained in almost optically pure form (>95% ee) after a single recrystallization.
Graphical abstractChiral 2-azanorbornyl-3-methanol is used as an organocatalyst for the highly enantioselective direct vinylogous Michael addition reaction of vinyl malononitriles to α,β-unsaturated aldehydes. In many cases, the products can be obtained in almost optically pure form (>95% ee) after a single recrystallization.Download full-size image
Related Topics
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Authors
Jun Lu, Feng Liu, Wei-Juan Zhou, Teck-Peng Loh,