| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273576 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Microwave irradiation facilitated the synthesis of 4-arylthio-3-oxazolin-5-ones from ethyl cyanoformate, thiophenol, and cyclic ketones. Subsequent decarboxylation and in situ [3+2] cycloaddition provided novel 2,3,4,5-tetrahydro-1H-pyrrolo[1,2-c][1,3]diazepine scaffolds after a spontaneous retro-Mannich domino reaction.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis of pyrrolo[1,3]diazepines by a dipolar cycloaddition-retro-Mannich domino reaction](/preview/png/5273576.png "First Page Preview: Synthesis of pyrrolo[1,3]diazepines by a dipolar cycloaddition-retro-Mannich domino reaction")
Authors
Mary Liang, Cecilia Saiz, Chiara Pizzo, Peter Wipf,