| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273698 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A copper triflate/t-BuOOAc-catalyzed amidation of allylic and benzylic acetates has been developed which is suitable for the coupling of a wide variety of functionalized sulfonamide nucleophiles with acetate electrophiles. The methodology allows for the amidation of benzylic substrates which are not further activated by an additional adjacent alkene or alkyne, enabling simple allylic acetates and primary benzylic acetates to be used as reaction partners.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David A. Powell, Guillaume Pelletier,