Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273709 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
An efficient metal-free catalytic protocol for the electrocyclization of α-alkoxydienones to cyclopentenones (Nazarov reaction) in near to quantitative yields is described. The key parameters are the use of inexpensive 4-toluenesulfonic acid in 5 mol % at room temperature in acetonitrile or under solvent-free conditions. The versatility of the transformation is demonstrated with unpolarized dienones with good regioselectivities and excellent yields.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mukkanti Amere, Jérôme Blanchet, Marie-Claire Lasne, Jacques Rouden,