| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273710 | Tetrahedron Letters | 2008 | 6 Pages |
Abstract
The effect of the arming-disarming protection in the acetolysis of 6-deoxy-sugar oligosaccharides has been for the first time systematically investigated. Starting from the newly synthesized methyl glycosides, the acetolysis conditions employed here afforded 1-O-Ac oligosaccharides selectively without cleavage of the interglycosidic bonds, if a suitable protecting group pattern was used. Actually, the behavior of armed-disarmed, armed-armed, and disarmed-disarmed 6-deoxy-sugar disaccharides in acetolysis reactions was investigated: the results fit well with the prediction made on the basis of the armed-disarmed effect.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Emiliano Bedini, Daniela Comegna, Annalida Di Nola, Michelangelo Parrilli,