Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273722 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde or a ketone, and diethyl phosphite catalyzed by Amberlite-IR 120 resin has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions. The major advantages of the present method are good yields, inexpensive, ecofriendly and reusable catalyst, mild and solvent-free reaction conditions and tolerance towards various functionalities present in the substrates.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Asish K. Bhattacharya, Kalpeshkumar C. Rana,