| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273735 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Glycosyl azides, prepared in situ from glucal and trimethylsilyl azide via Ferrier rearrangement, undergo smooth coupling with alkynes under neutral conditions by means of 'Click reactions' to furnish 1,2,3-triazole-linked glycoconjugates in high yields and with moderate stereoselectivity. The method provides a convenient route to prepare glycoconjugates from glucals, trimethylsilyl azide, and alkynes via a three component reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, D. Narasimha Chary, Ch. Suresh Reddy,