| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273808 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
A mild and efficient chlorination method for production of glycosyl chlorides is first described which employs inexpensive trichlorotriazine (TCT) and DMF as a chlorination reagent and is compatible with typical acid-labile hydroxyl protecting functions. The scope and limitations, reaction mechanism and its application in the sequential glycosylations are discussed.
Graphical abstractAn efficient preparation of glycosyl chlorides with the use of inexpensive trichlorotriazine (TCT) and DMF is first described.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chih-Wei Chang, Shih-Sheng Chang, Chin-Sheng Chao, Kwok-Kong T. Mong,