Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273873 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
Noyori's Ts-DPEN ligand bearing an amino sulfonamide moiety and with a primary amino group on a chiral scaffold was found to be a simple and efficient bifunctional organocatalyst for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins, which gave highly functional Michael adduct with quaternary stereocenters in good enantioselectivities (up to 84%ee) and dr (up to 5.7:1 dr).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ya-Dong Ju, Li-Wen Xu, Li Li, Guo-Qiao Lai, Hua-Yu Qiu, Jian-Xiong Jiang, Yixin Lu,