Article ID Journal Published Year Pages File Type
5273899 Tetrahedron Letters 2008 4 Pages PDF
Abstract

Oxonium ylides in situ generated from methyl phenyldiazoacetate and alcohols in the presence of CuPF6(CH3CN)4 underwent an aldol-type reaction with aldehydes or α-ketoesters in a convergent, three-component fashion to give α-alkoxyl-β-hydroxyl acid derivatives in good yields.

Graphical abstractOxonium ylides in situ generated from methyl phenyldiazoacetate and alcohols in the presence of CuPF6(CH3CN)4 underwent an aldol-type reaction with aldehydes or α-ketoesters in a convergent, three-component fashion to give α-alkoxyl-β-hydroxyl acid derivatives in good yields.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry