Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5273978 | Tetrahedron Letters | 2013 | 6 Pages |
Abstract
A palladium-catalyzed cross coupling of nitrogen bearing heterocyclic chloromethyl derivatives with aryl and heteroaryl boronic acids has been developed. In almost all cases, highly efficient cross-couplings were observed at ambient temperature, mitigating unwanted thermally induced side-reactions. The comprehensive substrate scope and respectable yields highlight the synthetic utility of this reaction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jason R. Schmink, Matthew T. Tudge,