| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5273984 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
Herein we describe our results on the synthesis and antioxidant properties of 4-arylchalcogenyl-7-chloroquinolines. This new class of compounds has been synthesized in high yields by the reaction of 4,7-dichloroquinoline with diaryl dichalcogenides using KOH as base, DMSO as solvent at 100 °C under air atmosphere and tolerates a range of substituents in the arylchalcogenyl moiety. The obtained compounds 3a and 3j were screened for in vitro antioxidant activity and the results demonstrated that compound 3j presented a potent antioxidant effect when compared to compound 3a.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lucielli Savegnago, Aline I. Vieira, Natália Seus, Bruna S. Goldani, Micheli R. Castro, Eder João Lenardão, Diego Alves,