| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274037 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The efficient synthesis of small molecules that collectively comprise optimal small-molecule screening collections is an important goal. With this in mind, we have used N-alkyl aziridines in a regio- and stereochemically controlled synthesis of polycyclic heterocycles based on nucleophilic ring opening and subsequent intramolecular cyclization.
Graphical abstractThe efficient synthesis of small molecules that collectively comprise optimal small-molecule screening collections is an important goal. With this in mind, we have used N-alkyl aziridines in a regio- and stereochemically controlled synthesis of polycyclic heterocycles based on nucleophilic ring opening and subsequent intramolecular cyclization.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alexander M. Taylor, Stuart L. Schreiber,