| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274040 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A one-pot, tandem process has been developed for the efficient synthesis of functionalised carbocyclic amides. A substituted cyclopentenyl trichloroacetamide was synthesised using a tandem thermal aza-Claisen rearrangement and RCM process, while an analogous cyclohexenyl trichloroacetamide was generated with high diastereoselectivity using a tandem MOM-ether directed metal-catalysed aza-Claisen rearrangement and RCM process.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michael D. Swift, Adele Donaldson, Andrew Sutherland,