| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274043 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
A variety of heterocyclic alcohols and acetates were coupled with silyl ketene acetals and other π-nucleophiles in the presence of trimethylsilyl trifluoromethanesulfonate to provide an array of substituted β-heteroaryl propionates, including those with contiguous quaternary centers, as well as vinylogs thereof. This reaction also proceeds with high diastereoselectivity when the π-nucleophile bears a chiral auxiliary.
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