| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274064 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The C18-C29 segment of amphidinolide F is synthesised in 12 steps from 1,4-butanediol. Key steps include a mono-Sharpless dihydroxylation of a dienoate, iodocyclisation to construct the trans-THF ring and an E-selective Wittig reaction to introduce the C25-C26 olefin.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alan Armstrong, Constantina Pyrkotis,