| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274094 | Tetrahedron Letters | 2009 | 4 Pages |
Based on the analysis of the mechanism of aerobic oxidation of alcohols using Ru(NO)-salen catalyst, we designed a new complex, Ru(PPh3)(OH)-salen 3, which was proved to be an excellent catalyst for chemoselective aerobic oxidation of primary alcohols to the aldehydes in the presence of secondary alcohols under ambient and non-irradiated conditions. Complex 3 was also successfully applied to the oxidation of 1-phenyl-1,n-diols to the lactols or the n-hydroxy aldehyde. It is of note that selective oxidation of primary alcohols was achieved even in the presence of activated secondary alcohols.
Graphical abstractWe have found that newly synthesized Ru(PPh3)(OH)-salen 3 is excellent catalyst for chemoselective aerobic oxidation of primary alcohols to the aldehydes even in the presence of activated secondary alcohols under ambient conditions.Download full-size image
