Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274121 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
Molybdenum trioxide (MoO3) catalyzed efficient oxidative cross-dehydrogenative-coupling (CDC) method for C-H functionalization of N-aryl tetrahydroisoquinolines has been explored. This user-friendly method of synthesizing α-aminophosphonates employs 1.1 equiv of dialkyl-H-phosphonate under aerobic condition. Formation of new C-P bonds from unfunctionalized starting materials under environmentally benign conditions provides an excellent avenue for the synthesis of biologically active α-aminophosphonates.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kaliyamoorthy Alagiri, Pradeep Devadig, Kandikere R. Prabhu,