| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274181 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Nucleophilic addition of alkyl- and aryl-zinc reagents to a C(4) functionalized isoxazolyl aldehyde proceeded effectively with high enantioselectivity (85–94% ee). The amino alcohol catalyst (S)-2-piperidinyl-1,1,2-triphenyl ethanol (10) afforded the (R)-product 2b, as established by X-ray crystallography.
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