| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274185 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A novel amphiphilic contrast agent, a GdPCTA-[12] derivative containing a dodecyl chain as lipophilic moiety, has been prepared. A convergent synthetic route from commercially available diethylene triamine and 3-hydroxypyridine is described. The target amphiphilic gadolinium complex was obtained in nine steps in 22% overall yield. Physicochemical properties and relaxivity measurements of this new contrast agent are described.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis of a novel amphiphilic GdPCTA-[12] derivative as a potential micellar MRI contrast agent](/preview/png/5274185.png "First Page Preview: Synthesis of a novel amphiphilic GdPCTA-[12] derivative as a potential micellar MRI contrast agent")
Authors
Clotilde Ferroud, Hélène Borderies, Elizabeth Lasri, Alain Guy, Marc Port,