Article ID Journal Published Year Pages File Type
5274219 Tetrahedron Letters 2008 5 Pages PDF
Abstract

Chiral pool approach using d-glucose, l-xylose, and d- and l-arabinoses was used to obtain four stereoisomeric 3-hydroxy-2-methylbutanoic acids with well defined configurations. The acids were isolated as fluorescent 2-naphthylmethyl esters after reaction with 2-naphthyldiazomethane.

Graphical abstractThe synthesis of the four stereoisomers of 3-hydroxy-2-methylbutanoic acid from carbohydrate precursors is described.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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