Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274219 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
Chiral pool approach using d-glucose, l-xylose, and d- and l-arabinoses was used to obtain four stereoisomeric 3-hydroxy-2-methylbutanoic acids with well defined configurations. The acids were isolated as fluorescent 2-naphthylmethyl esters after reaction with 2-naphthyldiazomethane.
Graphical abstractThe synthesis of the four stereoisomers of 3-hydroxy-2-methylbutanoic acid from carbohydrate precursors is described.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bogdan Doboszewski, Piet Herdewijn,