Article ID Journal Published Year Pages File Type
5274230 Tetrahedron Letters 2008 4 Pages PDF
Abstract

The chiral and stereoselective total synthesis of A-315675 1, an antiinfluenza agent, is described. The vicinal diamino moiety in 1 was stereoselectively constructed by the cascade Overman rearrangement of a vicinal allylic-homoallylic diol derived from d-tartrate.

Graphical abstractThe chiral and stereoselective total synthesis of A-315675 1, an antiinfluenza agent, is described. The vicinal diamino moiety in 1 was constructed in a one-step reaction by the cascade sequential Overman rearrangement of a vicinal allylic-homoallylic diol derived from d-tartrate.Download full-size image

Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , ,